BaAMPs

The database of Biofilm-active antimicrobial peptides

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BMAP-28 In solution Preformed biofilm
The project

Fight antimicrobial resistance

The first database dedicated to antimicrobial peptides (AMPs) specifically tested against microbial biofilms. The aim of this project is to provide useful resources for the study of AMPs against biofilms to microbiologist, bioinformatics researcher and medical scientist working in this field in an open-access framework.

Bacteriophages attacking Escherichia coli.
A natural community of bacteria growing on a single grain of sand. Image courtesy of the Lewis Lab at Northeastern University. Image created by Anthony D'Onofrio, William H. Fowle, Eric J. Stewart and Kim Lewis.
What is a biofilm?

Natural born killers

A biofilm is constituted of single or multiple organism species, such as fungi, bacteria, and viruses, encased in a self-secreted extracellular matrix. The treatment for biofilm infections is particularly challenging because bacteria in these conditions become refractory to antibiotic drugs.

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Antimicrobial peptides

A novel class of antimicrobial agents specialists

AMPs have been receiving increasing attention as potential therapeutic agents in infectious disease, presenting a wide spectrum of activity and a low rate in inducing microbial drug-resistance. In the last 10 years, interest in biofilm treatment by AMPs has been increasing dramatically.