General
| Peptide: | Esculentin-1a(1-21) |
| Microorganism: | Pseudomonas aeruginosa PAO1 / ATCC 15692 |
| Administration: | |
| Stage: | Preformed biofilm |
| Notes: |
Experimental procedure
| Method | AMP Effect(Biofilm reduction) | Concentration | Notes |
|---|---|---|---|
| Total countable CFUs | > 90% | 24 uM | |
| Total countable CFUs | 51 - 90% | 12 uM | |
| Total countable CFUs | 21 - 50% | 6 uM | |
| Total countable CFUs | <= 20 % | 1.5 uM |
Reference
- Vincenzo Luca, Annarita Stringaro, Marisa Colone, Alessandro Pini, Maria Luisa Mangoni Esculentin(1-21), an amphibian skin membrane-active peptide with potent activity on both planktonic and biofilm cells of the bacterial pathogen Pseudomonas aeruginosa
M. Di Luca, G. Maccari, G. Maisetta, G. Batoni BaAMPs: the database of biofilm-active antimicrobial peptides Biofouling 2015; 31(2):193-9.
Please do not hesitate to address comments or questions to: mariagrazia.diluca@nano.cnr.it or gpmaccari@gmail.com