General
| Peptide: | LF11-227 |
| Microorganism: | Pseudomonas aeruginosa PAO1 / ATCC 15692 |
| Administration: | |
| Stage: | Preformed biofilm |
| Notes: |
Experimental procedure
| Method | AMP Effect(Biofilm reduction) | Concentration | Notes |
|---|---|---|---|
| MTT assay | > 90% | 489.029 uM | |
| Crystal violet assay | 51 - 90% | 489.029 uM | |
| Total countable CFUs | >= 2 log | 489.029 uM | |
| Total countable CFUs | >= 1 log | 48.903 uM | |
| Total countable CFUs | >= 2 log | 97.806 uM | |
| Total countable CFUs | >= 3 log | 489.029 uM |
Reference
- Susana Sánchez-Gómez, Raquel Ferrer-Espada, Philip S. Stewart, Betsey Pitts, Karl Lohner, Guillermo Martínez de Tejada Antimicrobial activity of synthetic cationic peptides and lipopeptides derived from human lactoferricin against Pseudomonas aeruginosa planktonic cultures and biofilms
M. Di Luca, G. Maccari, G. Maisetta, G. Batoni BaAMPs: the database of biofilm-active antimicrobial peptides Biofouling 2015; 31(2):193-9.
Please do not hesitate to address comments or questions to: mariagrazia.diluca@nano.cnr.it or gpmaccari@gmail.com