#EXP00306

General

Accession EXP00306
Activity Adhesion (1-2h)
Date 2014-11-22
Administration Coated
Model in vitro
Organism Streptococcus sanguinis
Status Validated
Notes on titanium

Peptide

hLf1-11

GRRRRSVQWCA

Experimental activity

Method Concentration Notes
Total countable CFUs 100 uM physisorpted peptide
Total countable CFUs 200 uM physisorpted peptide
Total countable CFUs 50 uM Titanium silanizes with CPTES and coated with the peptide
Total countable CFUs 200 uM Titanium silanizes with CPTES and coated with the peptide
Total countable CFUs 50 uM Titanium silanizes with APTES and coated with the peptide
Total countable CFUs 100 uM Titanium silanizes with APTES and coated with the peptide

References

Covalent immobilization of hLf1-11 peptide on a titanium surface reduces bacterial adhesion and biofilm formation

Maria Godoy-Gallardo, Carlos Mas-Moruno, María C. Fernández-Calderón, Ciro Pérez-Giraldo, José M. Manero, Fernando Albericio, Francisco J. Gil, Daniel Rodríguez

2014. Acta Biomaterialia 8:3522-3534