#EXP00317

General

Accession EXP00317
Activity Preformed biofilm
Date 2014-12-01
Administration In solution
Model in vitro
Organism Staphylococcus aureus Smith diffuse SD)
Status Validated
Notes No notes

Peptide

BMAP-28

GGLRSLGRKILRAWKKYGPIIVPIIRI

Experimental activity

Method Concentration Notes
Total countable CFUs 5.207 uM MBC= The MBC was taken as the lowest concentration of each drug that resulted in no bacterial growth following removal of the peptide

References

Pre-treatment of central venous catheters with the cathelicidin BMAP-28 enhances the efficacy of antistaphylococcal agents in the treatment of experimental catheter-related infection

Oscar Cirioni, Andrea Giacometti, Roberto Ghiselli, Cristina Bergnach, Fiorenza Orlando, Federico Mocchegiani, Carmela Silvestri, Alberto Licci, Barbara Skerlavaj, Margherita Zanetti, Vittorio Saba, Giorgio Scalise

2006. Peptides 9:2104-2110