#EXP00323

General

Accession	EXP00323
Activity	Formation (3-24h)
Date	2014-12-01
Administration	Coated
Model	in vivo

Organism	Staphylococcus aureus Smith diffuse SD)
Status	Validated
Notes	Dacron graft

Peptide

FS8

YAPWTNA

Experimental activity

Method	Concentration	Notes
Total countable CFUs	12.175 uM	in rat

References

The Efficacy of the Quorum Sensing Inhibitor FS8 and Tigecycline in Preventing Prosthesis Biofilm in an Animal Model of Staphylococcal Infection

Oriana Simonetti, Oscar Cirioni, Federico Mocchegiani, Ivana Cacciatore, Carmela Silvestri, Leonardo Baldassarre, Fiorenza Orlando, Pamela Castelli, Mauro Provinciali, Marco Vivarelli, Erika Fornasari, Andrea Giacometti, Annamaria Offidani

2013. International Journal of Molecular Sciences 8:16321-16332